Small woodland tobacco, rat root, and Aloe arborescens. Grow your own: “Let food be your medicine and medicine your food.”

Neuroprotective potential of Aloe arborescens against copper induced neurobehavioral features of Parkinson’s disease in rat

The present investigation have brought, on the one hand, an experimental evidence of an altered dopaminergic innervations following Cu intoxication and on the other hand, a new pharmacological property of Aloe arborescens that may be used as a neuroprotective plant for neurodegenerative disorders, such as PD, touching the dopaminergic system trigged by heavy metals.


A Randomized Study of Chemotherapy VersusBiochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer

Aloe is one of the of the most important plants exhibiting anticancer activity and its antineoplastic property is due to at least three different mechanisms, based on antiproliferative, immunostimulatory and antioxidant effects.

The percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe arborescens than with chemotherapy alone, as well as the percent of 3-year survival patients.



Candelabra aloe (Aloe arborescens) in the therapy and prophylaxis of upper respiratory tract infections: traditional use and recent research results


Originally introduced to support the healing and recovery in cornea transplant patients, aqueous A. arborescens extracts soon became popular in the treatment of upper respiratory tract infections with a focus on toddlers and children. Recent preclinical and clinical data show that immunomodulatory, antiinflammatory, and antiviral effects contribute to its therapeutic efficacy.

In contrast, Aloe arborescens Miller (Candelabra Aloe) is characterized by a generally very low anthranoid content and is thus suited for other therapeutic purposes without
exerting laxative effects.

Secondary Phenol Metabolites (SPhMs), Distribution and Content of Some Aloe Species, Originated from Arid Zones of South Africa: A Review

Whole leaves of A. arborescens can be used as fresh food (Shioda et al., 2003). According to some studies, A. arborescensis richer than A. vera in respect to medicinal properties. The leaves of A. arborescens have long been used externally for therapeutic and cosmetic purposes. Experimentally, it has been demonstrated to exert a number of pharmacological effects (Suga and Hirata, 1983).

Barbaloin has been found to have a strong inhibitory effect on the histamine release from mast cells, while aloenin has a weak inhibitory effect. The inhibitory effect of barbaloin is much higher than that of a potent anti-inflammatory drug, such as Indomethaacin (Nakagomi et al., 1987).

Barbaloin content as a percentage of the dry weight of an Aloe arborescens leaf cut on 27 April 1993 and the consequent new growths from the same place on the plant cut on 27 May, 27 June and 27 July. The number above the column is the weight of the cut leaf (Gutterman and Chauser-Volfson, 2000a)

aloe arborescens phenol

The younger the leaf the denser is the vascular bundles and therefore the higher the content of the SPhMs.
Leaf pruning increase the content of the SPhMs in the leaves. The more times the plant is pruned the higher is the SPhMs content of its leaves, up to even 85% of the leaf dry weight.
Even pruning of one young leaf at the top part of the branch affect an increase in the leaves below. The closer the leaf below the one pruned, the higher the content of its’ SPhMs. The leaves oriented at the opposite side of the pruned leaf are also affected by increasing their content of SPhMs.